![]() In experimental laboratory work the New Zealand white rabbit is often used, as they are relatively large animals, which are easy to breed and keep. ![]() Many animals can be used to generate antibody, including sheep, goats, dogs and horses. They are also used as antivenoms, to treat dangerous snake bites, spider bites or jellyfish stings.Īntibodies cannot be made artificial means, and must be generated by an intact mammalian immune system. ![]() All vaccine research relies on the use of antibodies and they are frequently used for in vitro or culture work, and provide a valuable tool for identifying or locating any specific structure found in the blood. These molecules, generated by the immune specifically fit a target within the body, and are often used as biochemical markers or as methods of targeting drugs, as well as to study infectious agents or allergies. Antibody productionĪntibodies have many uses in medical research. Since the beginning of the 20th century, antibodies have been used to diagnose and treat illness, as well as providing the foundation for many experimental techniques. Antibodies can recognise and bind to many types of biochemical structures, including proteins, DNA, RNA, small chemicals, sugars and lipids. Antibodies are a type of protein released by B-cells of the immune system, and are responsible for the ability of the immune system to recognise specific foreign particles. Many other standard biomedical techniques which are used in research rely on the use of animals. These light chain types are identified as kappa and lambda chains.Only a small proportion of animals used in science are used for in vivo experiments on whole, living animals. The light chains found in immunoglobulins exist in two major forms. The differences in subclasses are based on small variations in the heavy chain units of antibodies in the same class. There are also a few subclasses of immunoglobulins in humans. The heavy chain type in IgE is an epsilon chain.
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